Original research 2015


The biology of appetite control: Do resting metabolic rate and fat-free mass drive energy intake?
Blundell JE, Finlayson G, Gibbons C, Caudwell P, Hopkins M.

Physiol Behav. 2015 Dec 1;152(Pt B):473-8. doi: 10.1016/j.physbeh.2015.05.031. No abstract available

The effect of encapsulated glutamine on gut peptide secretion in human volunteers. Meek CL, Lewis HB, Vergese B, Park A, Reimann F, Gribble F.
Peptides. 2015 Nov 2. pii: S0196-9781(15)00290-9. doi: 10.1016/j.peptides.2015.10.008. [Epub ahead of print]
PMID: 26541888

The Stomach-Derived Hormone Ghrelin Increases Impulsive Behavior. Anderberg RH, Hansson C, Fenander M, Richard JE, Dickson SL, Nissbrandt H, Bergquist F, Skibicka KP.
Neuropsychopharmacology. 2015 Oct 1. doi: 10.1038/npp.2015.297. [Epub ahead of print]
PMID: 26424164

Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine. Christensen LW, Kuhre RE, Janus C, Svendsen B, Holst JJ.
Physiol Rep. 2015 Sep;3(9). pii: e12551. doi: 10.14814/phy2.12551.
PMID: 26381015

Postprandial profiles of CCK after high fat and high carbohydrate meals and the relationship to satiety in humans.
Gibbons C, Finlayson G, Caudwell P, Webb DL, Hellström PM, Näslund E, Blundell JE.

Peptides. 2015 Sep 30. pii: S0196-9781(15)00270-3. doi: 10.1016/j.peptides.2015.09.010. [Epub ahead of print]
PMID: 26429068

Prolonged Adaptation to a Low or High Protein Diet Does Not Modulate Basal Muscle Protein Synthesis Rates - A Substudy.
Hursel R, Martens EA, Gonnissen HK, Hamer HM, Senden JM, van Loon LJ, Westerterp-Plantenga MS
. PLoS One. 2015 Sep 14;10(9):e0137183. doi: 10.1371/journal.pone.0137183. eCollection 2015.
PMID: 26367529

Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.
Steculorum SM, Paeger L, Bremser S, Evers N, Hinze Y, Idzko M, Kloppenburg P, Brüning JC.

Cell. 2015 Sep 10;162(6):1404-17. doi: 10.1016/j.cell.2015.08.032.
PMID: 26359991

Standardized food images: A photographing protocol and image database. Appetite.
Charbonnier L, van Meer F, van der Laan LN, Viergever MA, Smeets PA

2015 Sep 4;96:166-173. doi: 10.1016/j.appet.2015.08.041. [Epub ahead of print] . PMID: 26344127

Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells.
Pais R, Gribble FM, Reimann F.
Peptides. 2015 Jul 26. pii: S0196-9781(15)00215-6. doi: 10.1016/j.peptides.2015.07.019. [Epub ahead of print]
PMID: 26215048

Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin.
van der Plasse G, van Zessen R, Luijendijk MC, Erkan H, Stuber GD, Ramakers GM, Adan RA.
Int J Obes (Lond). 2015 Jul 17. doi: 10.1038/ijo.2015.131. [Epub ahead of print] PMID: 26183405

Functional MRI of Challenging Food Choices: Forced Choice between Equally Liked High- and Low-Calorie Foods in the Absence of Hunger.
Charbonnier L, van der Laan LN, Viergever MA, Smeets PA.
PLoS One. 2015 Jul 13;10(7):e0131727. doi: 10.1371/journal.pone.0131727. eCollection 2015.
PMID: 26167916

High fat diet impairs the function of glucagon-like peptide-1 producing L-cells. Richards P, Pais R, Habib AM, Brighton CA, Yeo GS, Reimann F, Gribble FM.
Peptides. 2015 Jul 3. pii: S0196-9781(15)00189-8. doi: 10.1016/j.peptides.2015.06.006. [Epub ahead of print]
PMID: 26145551

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells.
Moss CE, Glass LL, Diakogiannaki E, Pais R, Lenaghan C, Smith DM, Wedin M, Bohlooly-Y M, Gribble FM, Reimann F.
Peptides. 2015 Jul 2. pii: S0196-9781(15)00195-3. doi: 10.1016/j.peptides.2015.06.012. [Epub ahead of print]
PMID: 26144594

Perinatal overnutrition exacerbates adipose tissue inflammation caused by high-fat feeding in C57BL/6J mice. Kayser BD, Goran MI, Bouret SG.
PLoS One. 2015 Apr 2;10(3):e0121954. doi: 10.1371/journal.pone.0121954. eCollection 2015.
PMID: 25835281

Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling.
Dwarkasing JT, Boekschoten MV, Argilès JM, van Dijk M, Busquets S, Penna F, Toledo M, Laviano A, Witkamp RF, van Norren K. J
Cachexia Sarcopenia Muscle. 2015 Mar;6(1):84-94. doi: 10.1002/jcsm.12008. Epub 2015 Mar 31. PMID: 26136415

FTO is necessary for the induction of leptin resistance by high-fat feeding. Tung YC, Gulati P, Liu CH, Rimmington D, Dennis R, Ma M, Saudek V, O'Rahilly S, Coll AP, Yeo GS.
Mol Metab. 2015 Feb 7;4(4):287-98. doi: 10.1016/j.molmet.2015.01.011. eCollection 2015.
PMID: 25830092

Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine.
Kuhre RE, Frost CR, Svendsen B, Holst JJ.
Diabetes. 2015 Feb;64(2):370-82. doi: 10.2337/db14-0807. Epub 2014 Aug 25.

Targeting development of incretin-producing cells increases insulin secretion. Petersen N, Reimann F, van Es JH, van den Berg BM, Kroone C, Pais R, Jansen E, Clevers H, Gribble FM, de Koning EJ.
J Clin Invest. 2015 Jan;125(1):379-85. doi: 10.1172/JCI75838. Epub 2014 Dec 15. PMID: 25500886

Ghrelin programs development of hypothalamic feeding circuits
Steculorum SM, Collden G, Coupe B, Croizier S, Andrews Z, Jarosch F, Klussmann S, Bouret SG.

2015 The Journal of Clinical Investigation, 125(2): 846-858, 2015. doi: 10.1172/JCI73688
PMID: 25607843

Neonatal overnutrition causes early alterations in the central response to peripheral ghrelin
Collden G, Balland E, Parkash J, Caron E, Langlet F, Prevot V, Bouret SG.
Molecular Metabolism, 4(1):15-24, 2015. doi: 10.1016/j.molmet.2014.10.003
PMID: 25685686

Dietary Polyunsaturated Fatty Acids Increase Survival and Decrease Bacterial Load during Septic Staphylococcus aureus Infection and Improve Neutrophil Function in Mice
Svahn SL, Grahnemo L, Pálsdóttir V, Nookaew I, Wendt K, Gabrielsson B, Schéle E, Benrick A, Andersson N, Nilsson S, Johansson ME, Jansson JO.
Infect Immun 83:514-521. doi: 10.1128/IAI.02349-14
PMID: 25404025