Original research 2013


Tanycyte-Like Cells Form a Blood–Cerebrospinal Fluid Barrier in the Circumventricular Organs of the Mouse Brain.
Fanny Langlet, Amandine Mullier, Sebastien G. Bouret, Vincent Prevot, and Benedicte Dehouck.

J Comp Neurol. 2013 October 15; 521(15): 3389–3405. doi:10.1002/cne.23355. PMID: 23649873

Hypothalamic j-Opioid Receptor Modulates the Orexigenic Effect of Ghrelin
Amparo Romero-Picó, Maria J Vázquez, David González-Touceda, Cintia Folgueira, Karolina P Skibicka, Mayte Alvarez-Crespo, Margriet A Van Gestel, Douglas A Velásquez, Christoph Schwarzer, Herbert Herzog, Miguel López, Roger A Adan, Suzanne L Dickson, Carlos Diéguez and Rubén Nogueiras.

Neuropsychopharmacology (2013) 38, 1296–1307 doi:10.1038/npp.2013.28;

Comparison of Postprandial Profiles of Ghrelin, Active GLP-1, and Total PYY to Meals Varying in Fat and Carbohydrate and Their Association With Hunger and the Phases of Satiety
Catherine Gibbons, Phillipa Caudwell, Graham Finlayson, Dominic-Luc Webb, Per M. Hellström, Erik Näslund, and John E. Blundell.

J Clin Endocrinol Metab, May 2013, 98(5):E847–E855 doi: 10.1210/jc.2012-3835 PMID: 23509106

Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor
Eleftheria Diakogiannaki, Ramona Pais, Gwen Tolhurst, Helen E. Parker, James Horscroft, Beate Rausche,Tamara Zietek, Hannelore Daniel,Fiona M. Gribble & Frank Reimann

Diabetologia (2013) 56:2688–2696 doi: 10.1007/s00125-013-3037-3

Divergent circuitry underlying food reward and intake effects of ghrelin: Dopaminergic VTA-accumbens projection mediates ghrelin’s effect on food reward but not food intake
Karolina P. Skibicka, Rozita H. Shirazi, Cristina Rabasa-Papio, Mayte Alvarez-Crespo, Corinna Neuber, Heike Vogel, Suzanne L. Dickson.

Neuropharmacology 73 (2013) 274-283 doi:10.1016/j.neuropharm.2013.06.004

Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6
Shirazi R, Palsdottir V, Collander J, Anesten F, Vogel H, Langlet F, Jaschke A, Schürmann A, Prévot V, Shao R, Jansson JO, Skibicka KP

PNAS 2013 Sep 18 [Epub ahead of print] PMID 24048027

The gut microbiota reduces leptin sensitivity and the expression of the obesity suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous system
Schéle E, Grahnemo L, Anesten F, Hallén A, Bäckhed F, Jansson JO
Endocrinology 2013 Jul 26 [Epub ahead of print] PMID 23892476

Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting
Langlet F, Levin BE, Luquet S, Mazzone M, Messina A, Dunn-Meynell AA, Balland E, Lacombe A, Mazur D, Carmeliet P, Bouret SG, Prevot V, Dehouck B.

Cell Metabolism 17 (4) 2013 Apr 02 PMID 23562080

Role for the obesity-related FTO gene in the cellular sensing of amino acids
Gulati P, Cheung MK, Antrobus R, Church C, Harding HP, Tung YCL, Rimmington D, Ma M, Ron D, Lehner PJ, Ashcroft FM, Cox RD, Coll AP, O'Rahilly S, Yeo GSH
PNAS 2012 Dec 28 [Epub ahead of print] PMID 23359686

Protein leverage affects energy intake of high-protein diets in humans
Martens EA, Lemmens SG, Westerterp-Plantenga Ms
Am J Clin Nutr 2013 Jan [Epub ahead of print] PMID 23221572