Original research 2012


A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
Egerod KL, Engelstoft MS, Grunddal KV, Nøhr MK, Secher A, Sakata I, Pedersen J, Windeløv JA, Füchtbauer EM, Olsen J, Sundler F, Christensen JP, Wierup N, Olsen JV, Holst JJ, Zigman JM, Poulsen SS, Schwartz TW.
Endocrinology. 2012 Dec; 153(12):5782-95. doi: 10.1210/en.2012-1595. Epub 2012 Oct 12.
PMID: 23064014

Arcuate nucleus homeostatic systems are not altered immediately prior to the scheduled consumption of large, binge-type meals of palatable solid or liquid diet in rats and mice
Bake T, Duncan JS, Morgan DG, Mercer JG
Journal of Neuroendocrinology 2012 Nov 29 [Epub ahead of print] PMID 23194408

Resting metabolic rate is associated with hunger, self-determined meal size, and daily energy intake and may represent a marker for appetite
Caudwell P, Finlayson G, Gibbons C, Hopkins M, King N, Naslund E, Blundell JE
The American Journal of Clinical Nutrition 2012 Nov 28 [Epub ahead of print] PMID 23193010

A possible association between panic disorder and a polymorphism in the preproghrelin gene
Hansson C, Annerbrink K, Nilsson S, Bah J, Olsson M, Allgulander C, Andersch S, Sjoedin I, Eriksson E, Dickson SL
Psychiatry Research 2012 Oct 17 [Epub ahead of print] PMID 23084284

Food cues and ghrelin recruit the same neuronal circuitry
van der Plasse G, Merkestein M, Luijendijk MCM, van der Roest M, Westenberg HGM, Mulder AB, Adan RAH
International Journal of Obesity 2012 Oct 16 [Epub ahead of print] PMID 23069665

The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence
Alvarez-Crespo M, Skibicka KP, Farkas I, Molnar CS, Egecioglu E, Hrabovszky E, Liposits Z, Dickson SL
PLOS ONE 2012 Oct 10 PMID 23071554

Eating Behavior and GLP-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy
Johannessen H, Kodama Y, Zhao CM, Sousa MML, Slupphaug G, Kulseng B, Chen D
Obesity Surgery 2012 Sep 05 [Epub ahead of print] PMID 22949011

Contribution of the mesolimbic dopamine system in mediating the effects of leptin and ghrelin on feeding.
R. van Zessen, G. van der Plasse and R. A. H. Adan
Proc. Nut. Soc. (2012) 71: 435–445 doi:10.1017/S0029665112000614 PMID: 22800867

Alteration in neonatal nutrition causes perturbations in hypothalamic neural circuits controlling reproductive functio.
Caron E, Ciofi P, Prévot V, Bouret SG
Journal of Neuroscience 32 (33), 2012 Aug 15 PMID 22895731

Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
Habib AM, Richards P, Cairns LS, Rogers GJ, Bannon CA, Parker HE, Morley TC, Yeo GS, Reimann F, Gribble FM
Endocrinology 2012 Jun 08 [Epub ahead of print] PMID 22685263

Embryonic birthdate of hypothalamic leptin-activated neurons in mice
Ishii Y and Bouret SG
Endocrinology 2012 May 23 [Epub ahead of print] PMID 22621961

FTO expression is regulated by availability of essential amino acids
Cheung MK, Gulati P, O'Rahilly S, Yeo GS
Int J Obes 2012 May 22 [Epub ahead of print] PMID 22614055

Alteration in neonatal nutrition causes perturbations in hypothalamic neural circuits controlling reproductive function
Caron E, Ciofi P, Prevot V, Bouret SG
J Neurosci 2012 May 15 32 (33) PMID 22895731

The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors
Dickson SL, Shirazi RH, Hansson C, Bergquist F, Nissbrandt H, Skibicka KP
The Journal of Neuroscience 32 (14), 2012 Apr 04 PMID 22492036

Kinetic analysis of FTO (Fat mass and obesity related) reveals that it is unlikely to function as a sensor for 2-oxoglutarate
Ma M, Harding HP, O’Rahilly S, Ron D and Yeo GS
BJ Metabolism 444 (2), 2012 Mar [Epub ahead of print] PMID 22435707

Interleukin-6 Receptor α is Co-localised with Melanin-Concentrating Hormone in Human and Mouse Hypothalamus
Schéle E, Fekete C, Egri P, Füzesi T, Palkovits M, Keller E, Liposits Z, Gereben B, Karlsson-Lindahl L, Shao R, Jansson JO
J Neuroendocrinol, 2012 February [Accepted article ahead of print] PMID 22295972

Loss of Autophagy in Pro-opiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation
Coupé B, Ishii Y, Dietrich MO, Komatsu M, Horvath TL, Bouret SG
Cell Metabolism 15, 2012 February 08 [Epub ahead of print] PMID 22285542

Ghrelin Mediates Anticipation to a Palatable Meal in Rats
Merkestein M, Brans MA, Luijendijk MC, de Jong JW, Egecioglu E, Dickson SL, Adan RA
Obesity, 2012 January 26 [Epub ahead of print] PMID 22282050